NCT02835482

Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The use of the femtosecond laser causes an increase in the intraocular pressure (IOP) between 100 mm Hg and 200 mm Hg for a period of about 80 seconds (suction phase). If it is known that elevated IOP accelerates the degradation of retinal ganglion cells, whose axons form the optic nerve. No data has been published to date on potential adverse effects of femtolaser cataract surgery performed in patients with glaucomatous optic neuropathy. Since some time, spectral-domain optical coherence tomography (SD -OCT) provides a detailed analysis of ganglion cell complex (GCC) for which the loss is a marker of glaucomatous optic neuropathy. The resolution of this device, about a few microns, can detect even a tiny loss of this layer. The investigators propose to evaluate the effects of elevated intraocular pressure in glaucoma patients undergoing femtolaser cataract surgery, studying the GCC through SD-OCT.

Conditions

• Glaucoma
• Cataract

Interventions

Type	Name	Description
PROCEDURE	Femtolaser surgery
PROCEDURE	Phacoemulsification

Timeline

• Start date: 2016-04-14
• Primary completion: 2017-11-16
• Completion: 2017-11-16
• First posted: 2016-07-18
• Last updated: 2017-12-21

Locations

1 site across 1 country: France