Clinical Trials Directory

Trials / Completed

CompletedNCT02833142

Pharmacokinetics, Safety and Tolerability of Single Doses of BIIB033 (Opicinumab) Produced by 2 Manufacturing Processes

A Randomized, Blinded, Parallel-Group, Phase 1 Study of Pharmacokinetics, Safety and Tolerability of Single Intravenous Doses of BIIB033 (Opicinumab ) Produced by 2 Manufacturing Processes, in Healthy Volunteers

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
28 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The primary objective of the study is to characterize the pharmacokinetics (PK) of BIIB033-B and to compare the PK profile with that of BIIB033-A in healthy volunteers. Secondary objectives are: To assess the safety and tolerability of BIIB033-A and BIIB033-B; To assess the secondary PK parameters of BIIB033-A and BIIB033-B; To assess the immunogenicity of BIIB033-A and BIIB033-B.

Conditions

Interventions

TypeNameDescription
DRUGBIIB033 (opicinumab)

Timeline

Start date
2016-07-01
Primary completion
2016-11-01
Completion
2016-11-01
First posted
2016-07-14
Last updated
2016-12-08

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02833142. Inclusion in this directory is not an endorsement.

Pharmacokinetics, Safety and Tolerability of Single Doses of BIIB033 (Opicinumab) Produced by 2 Manufacturing Processes (NCT02833142) · Clinical Trials Directory