NCT02816502

Hippocampal Plasticity of Young Adults With Childhood Adversity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 73 (actual)
• Sponsor: Mclean Hospital · Academic / Other
• Sex: All
• Age: 21 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This study investigates the clinical and neural effects of stress management skill building programs for young adults with childhood adversity. The investigators will recruit a total of 60 young adults (21-35 years old) who will be randomized into two different stress management skill building programs, both of which are 8 weeks long. MRI and psychological assessments will be acquired from all subjects before and after the intervention programs in order to investigate changes in clinical symptoms (such as depression, anxiety and stress) and hippocampus structure and function as well as other neural changes.

Conditions

• Depression
• Anxiety

Interventions

Type	Name	Description
BEHAVIORAL	Stress Management Skill Building Program A	Subject will meet with the instructor and other students in the group once a week and complete homework and track amount of practice during the week.
BEHAVIORAL	Stress Management Skill Building Program B	Subject will meet with the instructor and other students in the group once a week and complete homework and track amount of practice during the week.

Timeline

• Start date: 2017-06-15
• Primary completion: 2018-12-01
• Completion: 2020-07-07
• First posted: 2016-06-28
• Last updated: 2021-03-25

Locations

1 site across 1 country: United States