Clinical Trials Directory

Trials / Completed

CompletedNCT02813967

S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer

S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Chinese Patients With Squamous Cell Carcinoma of Esophagus: A Prospective, Randomized, Multi-center Phase-III Study

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
298 (actual)
Sponsor
Zhejiang Cancer Hospital · Academic / Other
Sex
All
Age
70 Years – 85 Years
Healthy volunteers
Not accepted

Summary

This was a randomised, multicenter, phase 3 trial. Patients who were age of 70 years or older with histologically confirmed esophageal cancer were randomly assigned to S-1 concurrent with radiotherapy or radiotherapy alone.The primary endpoint was overall survival.

Conditions

Interventions

TypeNameDescription
RADIATIONRadiotherapy 54 GyRadiotherapy was administered in 1.8 Gy fractions 5 times weekly to a total dose of 54 Gy.
RADIATIONRadiotherapy 60 GyRadiotherapy was administered in 2 Gy fractions 5 times weekly to a total dose of 60Gy.
DRUGS-1S-1 70mg/m2 was administered on days 1-14 and 29-42.

Timeline

Start date
2016-06-01
Primary completion
2020-08-01
Completion
2020-08-01
First posted
2016-06-27
Last updated
2020-09-16

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT02813967. Inclusion in this directory is not an endorsement.