NCT02812563

Familial Analysis of Keratoconus Risk

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 95 (actual)
• Sponsor: University Hospital, Bordeaux · Academic / Other
• Sex: All
• Age: 7 Years
• Healthy volunteers: Accepted

Summary

The principal objective of this study is to evaluate the frequency of KC inside family of patients with confirmed KC. It's a familial, epidemiological, prospective, single-center study.

Detailed description

Keratoconus is a common bilateral progressive corneal ectatic disease causing visual impairment by inducing irregular astigmatism and corneal opacities. This disorder typically begins during teenage years, progresses until the age of 30 to 40 years and, in severe forms, may need a corneal transplantation. Currently, keratoconus has not known etiopathogenesis, and it is difficult to detect subclinical forms. Several risk factors seem to be implied, environmental and genetic : the risk of keratoconus in case of familial history of keratoconus isn't well known at that time, but seems to be important to consider to promote screening and follow up of patient with a familial history of keratoconus (KC).

Conditions

• Keratoconus

Interventions

Type	Name	Description
OTHER	genetic	Galilee exam - Corn analysis with Optiwave Refractive Analysis

Timeline

• Start date: 2014-11-25
• Primary completion: 2017-09-19
• Completion: 2017-09-19
• First posted: 2016-06-24
• Last updated: 2017-11-13

Locations

1 site across 1 country: France