NCT02802150

The Effect of Oral Zanthoxylum Schinifolium Seed Oil in Individuals With Dry Eye Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Chonbuk National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the clinical efficacy and safety of 10-weeks oral consumption of Zanthoxylum schinifolium seed Oil (ZSO) in patients with mild dry eye disease.

Detailed description

In this double-blind, randomized and placebo-controlled trial, twenty participants experiencing dry eyes symptoms were recruited, and randomly assigned to consume 4 g/day of either ZSO or soy bean oil (SBO) as placebo for 10 weeks. All participants completed the study. Follow-ups of dry eye symptoms and objective signs, inflammatory and oxidative stress markers, and blood lipid analysis were performed.

Conditions

• Dry Eye Syndromes

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Zanthoxylum Schinifolium Seed Oil(4g/day)	parallel design
DIETARY_SUPPLEMENT	Soy Bean Oil;placebo(4g/day)	parallel design

Timeline

• Start date: 2015-02-01
• Primary completion: 2015-07-01
• Completion: 2016-02-01
• First posted: 2016-06-16
• Last updated: 2016-06-16

Locations

2 sites across 1 country: South Korea