NCT02788370

Cardiopulmonary Response to Conical-PEP Breathing During Exercise in Older People.

Cardiopulmonary Response to Conical Positive Expiratory Breathing During Exercise in Older People.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Khon Kaen University · Academic / Other
• Sex: All
• Age: 60 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Aim of this study is to compare cardiopulmonary response to conical-PEP breathing during exercise in older people.

Detailed description

It is known that all most structures and physiological functions deteriorate with age, leading to decrease exercise performance, functional decline and gradual decrease of physical activity in aging. The most essential change of respiratory physiology are: dilatation of alveoli, enlargement of air space, decrease gas exchange surface area, loss of supporting tissue for distal airway (senile emphysema), decrees of chest wall compliance and decrease of respiratory muscle strength. These changes leading to decrease lung elastic recoil, increase residual volume and functional capacity, and increase work of breathing at rest. In addition, such changes affect respiratory function, especially dynamic hyperinflation (DH) development which could be one of the factors relate to dyspnea during exercise in aging Positive expiratory pressure (PEP) therapy for DH treatment during exercise was reported in several studies. It is possible that PEP breathing may improve cardiopulmonary response to exercise in older people.

Conditions

• Aging

Interventions

Type	Name	Description
DEVICE	a conical positive expiratory pressure device	The CPEP device will be connected to respiratory transducer for generating positive expiratory pressure with therapeutic rang (5 to 20 cm H2O).
OTHER	Constant work load cycling test	Participants will per form constant work load cycling test until symptom limit with 50 to 60 rpm. The termination criteria include 1. sever breathlessness (\>5 /10 score of modified Borg scale) 2. leg fatigue (can not maintain speed between 50 to 60 rpm) 3. Hear rate (HR) \>80 % age-predicted maximum HR 4. Exercise time up to 10 minutes 5. Other symptom that stated by American thoracic Society(2002)

Timeline

• Start date: 2016-07-01
• Primary completion: 2016-11-01
• Completion: 2017-12-01
• First posted: 2016-06-02
• Last updated: 2017-08-22