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UnknownNCT02784847

A Pilot Trial of Triheptanoin for the Preventive Treatment of Migraine

Status
Unknown
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
10 (estimated)
Sponsor
University of Liege · Academic / Other
Sex
Female
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

A pilot trial of triheptanoin, a natural compound able to promote anaplerotic mitochondrial metabolism, for the preventative treatment of migraine.

Detailed description

To test the ability of a daily 3-month treatment with triheptanoin to prevent migraine attacks in 10 migraine patients. This is an open, non-randomized pilot trial that might justify a placebo-controlled trial, if there are at least 50% of patients with ≥50% reduction in attack frequency.

Conditions

Interventions

TypeNameDescription
DRUGTriheptanoinTriheptanoin oil administered three times per day during meals at a total dose 1mg/kg/day for 3 months

Timeline

Start date
2016-06-01
Primary completion
2016-11-01
Completion
2016-11-01
First posted
2016-05-27
Last updated
2016-05-27

Source: ClinicalTrials.gov record NCT02784847. Inclusion in this directory is not an endorsement.

A Pilot Trial of Triheptanoin for the Preventive Treatment of Migraine (NCT02784847) · Clinical Trials Directory