Trials / Completed
CompletedNCT02775682
Cerebral Autoregulation in Patients With Epilepsy
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 200 (actual)
- Sponsor
- Yi Yang · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine whether patients with epilepsy exhibiting impaired dCA, which may contribute to subsequent stroke.
Detailed description
The relationship between epileptic seizures and cerebrovascular disease is complex, ranging from mechanisms to clinical manifestation. Stroke is one of the most common causes of epilepsy in adulthood. It was also reported that patients with epilepsy exhibited a higher risk of stroke. But its potential mechanism was never fully understood. Dynamic cerebral autoregulation(dCA), a mechanism to maintain the cerebral bold flow, has been proved to be critical for the occurrence ,development and prognosis of ischemic neurovascular disease. In this study, we hypothesis that impaired dCA play a role in epilepsy and subsequent stroke.
Conditions
Timeline
- Start date
- 2016-04-01
- Primary completion
- 2017-05-01
- Completion
- 2017-05-01
- First posted
- 2016-05-18
- Last updated
- 2021-08-25
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02775682. Inclusion in this directory is not an endorsement.