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CompletedNCT02767050

Incidence of Caries in Smoking and Smokeless Tobacco

Incidence of Caries in Smoking and Smokeless Tobacco-An Observation Study

Status
Completed
Phase
Study type
Observational
Enrollment
613 (actual)
Sponsor
Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre · Academic / Other
Sex
All
Age
15 Years – 100 Years
Healthy volunteers
Accepted

Summary

The following observational study evaluates incidence of caries in smoking and smokeless tobacco based on habit history by clinical examination and DMFT index.

Detailed description

Dental caries is an irreversible microbial disease of the calcified tissues of the teeth, characterized by demineralization of the inorganic portion and destruction of the organic substance of the tooth, which often leads to cavitation. It is a complex and dynamic process where a multitude of factors influence and initiate the progression of disease. There are practically no geographic areas in the world whose inhabitants do not exhibit some evidence of dental caries. It affects persons of both genders in all races, all socioeconomic strata and every age group. Likewise, there is strong evidence that tobacco use has numerous negative effects on oral health, for example staining of teeth, dental restoration, development of oral diseases. A biologically reasonable explanation for an association between chewing tobacco use and dental caries may be the presence of higher levels of fermentable sugars in chewing tobacco products which can stimulate the growth of carcinogenic bacteria. The decreased buffering effect possible lower pH of smokers saliva and higher number of lactobacilli and streptococcus mutans group may indicate an increased susceptibility to caries in smokers. On the other hand, there are researches which conclude that presence of extrinsic tobacco stains appear to provide a protective effect from caries.

Conditions

Timeline

Start date
2015-12-01
Primary completion
2015-12-01
Completion
2016-02-01
First posted
2016-05-10
Last updated
2016-05-11

Locations

1 site across 1 country: India

Source: ClinicalTrials.gov record NCT02767050. Inclusion in this directory is not an endorsement.

Incidence of Caries in Smoking and Smokeless Tobacco (NCT02767050) · Clinical Trials Directory