NCT02750657

Study of Changes and Characteristics of Genes in Patients With Pancreatic Cancer for Better Treatment Selection

Comprehensive Molecular Characterization of Advanced Pancreatic Ductal Adenocarcinomas (PDAC) for Better Treatment Selection: A Prospective Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 332 (actual)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Researchers are looking for better ways of understanding and treating pancreatic cancer. The purpose of this study is to see how useful it is to look for changes and characteristics in your genes (molecules that contain instructions for the development and functioning of the cells) and the genes within the tumour. These characteristics may be useful in choosing treatments for patients in the future. Changes (mutations) in genes have been shown to be an important characteristic in cancers. Looking at differences in genes in patients with advanced pancreatic ductal adenocarcinomas and comparing this information with response to their initial chemotherapy treatment may help to learn which treatments may be better for certain patients after initial treatment.

Conditions

• Carcinoma, Pancreatic Ductal

Interventions

Type	Name	Description
GENETIC	Molecular Profiling	Whole Genome Sequencing

Timeline

• Start date: 2015-12-01
• Primary completion: 2025-08-01
• Completion: 2025-08-01
• First posted: 2016-04-25
• Last updated: 2025-11-18

Locations

4 sites across 1 country: Canada