NCT02748070

Perioperative Oral Steroids for Chronic Rhinosinusitis Without Polyps (CRSsNP)

The Role of Perioperative Systemic Steroids in Patients With Chronic Rhinosinusitis Without Polyps (CRSsNP)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 81 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

While oral steroids have been shown to be effective in the management of patients with chronic rhinosinusitis with polyps, its role in treating chronic rhinosinusitis without polyps (CRSsNP) is ambiguous. Despite a lack of strong clinical evidence to suggest a benefit in this disease state, steroids are often prescribed as a component of post-operative care after sinus surgery for patients without polyps. Oral steroids carry with them significant adverse effects, and should be prescribed thoughtfully. The aims of this study are to determine if oral steroids in the peri-operative period improves patient outcomes in CRS without polyps.

Conditions

• Chronic Rhinosinusitis
• Endoscopic Sinus Surgery
• Chronic Rhinosinusitis Without Polyps
• Oral Steroids

Interventions

Type	Name	Description
DRUG	Prednisone
DRUG	Flonase

Timeline

• Start date: 2015-08-01
• Primary completion: 2019-07-15
• Completion: 2019-07-15
• First posted: 2016-04-22
• Last updated: 2020-08-04
• Results posted: 2020-07-24

Locations

1 site across 1 country: United States