NCT02737215

Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting in Patients With Obstructive Sleep Apnea

Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting in Patients With Obstructive Sleep Apnea: a Multicenter Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 144 (actual)
• Sponsor: Rodrigo Pinto Pedrosa · Academic / Other
• Sex: All
• Age: 30 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Background. Atrial fibrillation is one of the most common complications in the postoperative period of coronary artery bypass grafting (CABG) surgery and usually associated with increased length of hospital stay and higher hospital costs. Among the main mechanisms involved, excessive sympathetic activation, oxidative stress and inflammation are fundamental elements in the pathophysiology of obstructive sleep apnea. Objectives. To evaluate the effects of continuous positive airway pressure (CPAP) in reduction of atrial fibrillation after CABG in patients with obstructive sleep apnea. Methodological procedures: A multicenter randomized controlled study to compare the incidence of atrial fibrillation between the intervention group and the control group, both monitored seven days with Holter.

Conditions

• Atrial Fibrillation
• Obstructive Sleep Apnea
• Coronary Artery Bypass Grafting

Interventions

Type	Name	Description
DEVICE	CPAP	patients will receive CPAP therapy with Auto-CPAP

Timeline

• Start date: 2016-05-02
• Primary completion: 2019-12-01
• Completion: 2019-12-01
• First posted: 2016-04-13
• Last updated: 2021-12-09

Locations

3 sites across 1 country: Brazil