Trials / Completed
CompletedNCT02726906
Lifestyle Enriching Activities for Research in Neuroscience Intervention Trial: LEARNit Study
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 66 (actual)
- Sponsor
- University of Southern California · Academic / Other
- Sex
- All
- Age
- 55 Years – 80 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to examine the effects of modifiable lifestyle factors including exercise and healthy living on brain health. The investigators will compare 2 types of interventions, moderate aerobic walking vs. healthy living education, over 6 months to evaluate changes in brain health, cognition, and physical function in older adults with cognitive concerns.
Detailed description
Cognitive decline in older adults is a major public health issue. The cost of caring for older adults with substantial cognitive impairment, like those with Alzheimer's Disease in the US is approximately $200 billion a year, causing major societal, economic, and caregiving burden. Despite great advances towards diagnosing these problems, the discovery of effective treatments has been minimal. Exploring non-pharmacological interventions, such as exercise and healthy living, have gained momentum. These promising, modifiable lifestyle interventions have the potential for delaying disease onset and slowing decline in cognition. However, the therapeutic effect of lifestyle interventions in patients with mild cognitive impairment, a prime intervention period for treatment, is not well understood. Therefore, in this study, the investigators will examine brain, body, and cognitive changes in older adults who engage in moderate-aerobic walking or healthy living education.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Moderate-aerobic walking | |
| RADIATION | Positron Emission Tomography (PET) scan | Radioligand that binds to proteins using a PET/CT scanner. |
| BEHAVIORAL | Healthy living education | |
| DEVICE | Physical activity monitor | Wrist device that will track daily physical activity |
Timeline
- Start date
- 2016-08-21
- Primary completion
- 2022-07-13
- Completion
- 2022-07-15
- First posted
- 2016-04-04
- Last updated
- 2024-10-02
- Results posted
- 2024-09-19
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02726906. Inclusion in this directory is not an endorsement.