Clinical Trials Directory

Trials / Terminated

TerminatedNCT02715466

Gelatin in ICU and Sepsis

Prospective, Controlled, Double-Blind, Randomized Multicentric Study On The Efficacy And Safety Of An Early Target Controlled Plasma Volume Replacement Therapy With A Balanced Gelatine Solution vs A Balanced Electrolyte Solution In Patients With Severe Sepsis

Status
Terminated
Phase
Phase 4
Study type
Interventional
Enrollment
167 (actual)
Sponsor
B. Braun Melsungen AG · Industry
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

This prospective, double-blind randomized controlled trial evaluates the differences in terms of efficacy and safety of gelatin based resuscitation as compared to crystalloid based resuscitation in two parallel groups of patients with severe sepsis / septic shock.

Conditions

Interventions

TypeNameDescription
DRUGBalanced gelatine solutionGelaspan combined with Sterofundin ISO
DRUGBalanced electrolyte solutionSterofundin ISO

Timeline

Start date
2016-04-01
Primary completion
2021-12-08
Completion
2021-12-08
First posted
2016-03-22
Last updated
2025-08-19
Results posted
2025-08-19

Locations

12 sites across 5 countries: Austria, Czechia, France, Germany, Spain

Source: ClinicalTrials.gov record NCT02715466. Inclusion in this directory is not an endorsement.