NCT02715271

Study of TB Lesions Obtained in Therapeutical Surgery

Study of TB Lesions Obtained in Surgery: in Search of Best Biomarkers Correlating With TB Pathology, Clinical Features, MDR Cases and Prognostic

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 192 (actual)
• Sponsor: Fundació Institut Germans Trias i Pujol · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The correlation of the morphologic, microbiological, genetic and histopathological characteristics of TB lesions obtained in therapeutical surgery with the clinical forms and features of the patients will provide essential information 1. on the role of the host in the mechanisms associated to the generation and evolution of active TB and 2. about future diagnostic and/or prognostic biomarkers of TB disease. All this information could be used for patients stratification and/or to design new therapeutic strategies.

Conditions

• Tuberculosis
• Thoracic Surgery
• Tuberculosis, Pulmonary
• Tuberculosis, Multidrug-Resistant

Interventions

Type	Name	Description
PROCEDURE	therapeutical surgery for TB	Patients undergoing therapeutical surgery for tuberculosis (DS- and MDR/XDR-TB) indicated as per clinical routine

Timeline

• Start date: 2016-09-01
• Primary completion: 2024-05-01
• Completion: 2024-05-01
• First posted: 2016-03-22
• Last updated: 2025-03-11

Locations

1 site across 1 country: Georgia