NCT02710461

Grape and Pomegranate Polyphenols in Postprandial Glucose and Related Parameters

Acute Effects of Grape and Pomegranate Polyphenols as Modulators of Metabolic Syndrome in Humans

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: National Research Council, Spain · Other Government
• Sex: All
• Age: 40 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The aim of this is study is to evaluate the acute effect of grape and pomegranate polyphenols in the modulation of markers of metabolic syndrome. Most of the previous works about polyphenols have only considered a fraction of polyphenols, i.e., extractable polyphenols. As a consequence, an important amount of dietary polyphenols, the so-called non-extractable polyphenols are ignored. In contrast, the effect of both extractable and non-extractable polyphenols will be considered in this study. Furthermore, the effect of both polyphenols as present in the food matrix and metabolites derived from microbial fermentation will be evaluated.

Conditions

• Subjects With Abdominal Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Mixture of grape pomace and pomegranate pomace	Oral Glucose Tolerance Test
DIETARY_SUPPLEMENT	Mixture of grape pomace and pomegranate pomace	Oral Glucose Tolerance Test right after taking the mixture of grape and pomegranate polyphenols
DIETARY_SUPPLEMENT	Mixture of grape pomace and pomegranate pomace	Oral Glucose Tolerance Test ten hours after taking the mixture of grape and pomegranate polyphenols

Timeline

• Start date: 2016-03-01
• Primary completion: 2016-10-01
• Completion: 2016-12-01
• First posted: 2016-03-16
• Last updated: 2017-03-28

Locations

1 site across 1 country: Spain