Clinical Trials Directory

Trials / Terminated

TerminatedNCT02709811

Safety and Feasibility of Electrochemotherapy in Unresectable Colorectal Adenocarninoma Liver Metastases

Safety and Feasibility of Electrochemotherapy in the Treatment of Unresectable Liver Metastases From Colorectal Adenocarninoma

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
5 (actual)
Sponsor
IGEA · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Electrochemotherapy (ECT) is a non-thermal tumour ablation modality. It consists of the local potentiation, by means of local reversible electroporation of tumour tissues, of the antitumor activity of non-permeant or poorly permeant anticancer drugs already possessing intrinsic cytotoxicity. ECT has proved to be effective in the treatment of various cutaneous tumour nodules of any origin. Mostly ECT is offered to patients in case of multiple cutaneous metastases, when they cannot be excised, due to their number or localization. This study investigate the application of ECT in the treatment of liver metastases from colorectal adenocarcinoma, for which other thermal cytoreductive methods would be risky compared to the supposed expected clinical benefits.

Conditions

Interventions

TypeNameDescription
DRUGElectrochemotherapy

Timeline

Start date
2012-08-01
Primary completion
2015-01-01
Completion
2015-01-01
First posted
2016-03-16
Last updated
2016-03-16

Source: ClinicalTrials.gov record NCT02709811. Inclusion in this directory is not an endorsement.