NCT02702726

The Oil, Fats and Oleogel Study

The Oil, Fats and Oleogel (OFO) Study: Effects of Dietary Fats, Ingested in Two Physical Forms, on Acute Human Energy Balance, Appetitive and Glycemic Responses

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Singapore Institute of Food and Biotechnology Innovation · Other Government
• Sex: Male
• Age: 21 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to compare the effects of dietary fats, ingested in two physical forms, on acute energy balance, appetitive, and glycemic responses of healthy normal (BMI 18-24.9 kgm-2) or overweight (BMI\>25kgm-2) adults.

Detailed description

This will be a randomised, crossover study. Randomisation will be performed with an online randomisation software (www.randomizer.org). Participants will be screened (1 screening visit) and attend five test visits conducted in a whole room calorimeter (WRC). During each test visit, participants will arrive at the laboratory after an overnight fast, enter the WRC and rest for 15 minutes in a supine position,have their resting energy expenditure (REE) measured for 30 minutes and consume congee and juice alone(control), or with one of the 4 dietary fats: sunflower oil (SO) or gel (SG) and coconut oil (CO) or gel (CG) (total 5 test visits). Post-meal energy expenditure, fat oxidation, glycemia and appetite (visual analog scales) will be measured continuously for 3 hours in WRC, followed by a meal challenge where participants will eat until sated. Participants will return and repeat the protocol until all fat types and forms are completed.

Conditions

• Glycaemic Response and Energy Balance

Interventions

Type	Name	Description
OTHER	Congee and juice with coconut gel	25g coconut oleogel
OTHER	Congee and juice with coconut oil	25g coconut oil
OTHER	Congee and juice with sunflower gel	25g sunflower oleogel
OTHER	Congee and juice with sunflower oil	25g sunflower oil

Timeline

• Start date: 2016-01-12
• Primary completion: 2017-05-23
• Completion: 2017-05-23
• First posted: 2016-03-09
• Last updated: 2017-08-23

Locations

1 site across 1 country: Singapore