NCT02700711

Methylphenidate-Duloxetine Combinations for Cocaine Dependence

Randomized Clinical Trial: 03 (Methylphenidate and Duloxetine)

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: University of Kentucky · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study will determine the influence of methylphenidate (e.g., Ritalin®) and duloxetine (Cymbalta®), alone and in combination, on the cocaine use as measured by self-report and urine drug screens.

Conditions

• Cocaine Use Disorder

Interventions

Type	Name	Description
DRUG	Methylphenidate	The pharmacodynamic effects of methylphenidate maintenance will be determined during maintenance on placebo and duloxetine.
DRUG	Placebo	The pharmacodynamic effects of placebo will be determined during maintenance on placebo and duloxetine.
DRUG	Duloxetine	The pharmacodynamic effects of duloxetine will be determined during maintenance on placebo and methylphenidate

Timeline

• Start date: 2016-02-01
• Primary completion: 2018-06-01
• Completion: 2018-06-01
• First posted: 2016-03-07
• Last updated: 2018-06-26

Locations

1 site across 1 country: United States