NCT02699827

Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia

Adding Magnesium Sulphate to Epidural Levobupivacaine in Elective Caesarian Section for Patients With Preeclampsia

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Mohamed Sayed Abdelhafez · Academic / Other
• Sex: Female
• Age: 20 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective caesarian section (CS).

Detailed description

Pregnant women with preeclampsia undergoing elective CS in will be included in the study. All patients participating in the study will be randomly divided into two groups; magnesium sulphate group (study group) and placebo group (control group). Patients in the study group will receive epidural 20 ml levobupivacaine hydrochloride 0.5% plus 5 ml magnesium sulphate 10% (500 mg) while patients in the control group will received epidural 20 ml levobupivacaine hydrochloride 0.5% plus 5 ml saline 0.9%.

Conditions

• Preeclampsia

Interventions

Type	Name	Description
DRUG	Levobupivacaine hydrochloride	Patients will receive epidural 20 ml levobupivacaine hydrochloride 0.5%
DRUG	Magnesium sulphate	Patients will receive epidural 5 ml magnesium sulphate 10%
DRUG	Saline 0.9%	Patients will receive epidural 5 ml saline 0.9%

Timeline

• Start date: 2016-03-01
• Primary completion: 2017-01-01
• Completion: 2017-01-01
• First posted: 2016-03-04
• Last updated: 2017-06-06

Locations

1 site across 1 country: Egypt