NCT02698709

Astigmatic Vector Analysis of Posterior Cornea - a Comparison Among Healthy, Forme Fruste and Overt Keratoconus Corneas

Astigmatic Vector Analysis of Posterior Corneal Surface - a Comparison Among Healthy, Forme Fruste and Overt Keratoconus Corneas

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 698 (actual)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The main purpose of this study is to determine new diagnostic criteria for an eye disease called keratoconus.

Detailed description

Eyes of patients who distinctly present signs of keratoconus, for both eyes, at corneal tomography (an exam commonly used in such cases), and those who present such signs in only one eye were compared to eyes of unaffected patients. Several characteristics of anterior and posterior corneal astigmatism (special emphasis was given to the latter) were collectively assessed among all patients by a method referred to as vectorial analysis. Statistical tests were then performed, in an attempt to highlight differences among those three groups of patients and, eventually, define new diagnostic criteria.

Conditions

• Keratoconus

Interventions

Type	Name	Description
OTHER	Analysis of anterior and posterior corneal surfaces	Corneal data obtained from a Scheimpflug-based topographer were converted to astigmatic vectors in accordance to the method proposed by Thibos

Timeline

• Start date: 2015-05-01
• Primary completion: 2015-08-01
• Completion: 2015-09-01
• First posted: 2016-03-04
• Last updated: 2016-03-04

Locations

1 site across 1 country: Brazil