NCT02678845

Project Collabri for Treatment of Depression

Project Collabri. The Effect of a Collaborative Care Model for Treatment of Depression in Primary Care in Denmark - A Cluster Randomized Clinical Superiority Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 325 (actual)
• Sponsor: Amager Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether treatment of patients with depression according to the Collabri Model is more effective in reducing symptoms compared to treatment as usual (TAU)

Detailed description

Background: Depression is a common disease mostly treated in general practice. Diagnose and evidence based treatment in general practice today is not optimal (e.g. lack of continuity in disease management and lack of treatment opportunities). International studies show effect of collaborative care on depression, but is not directly applicable into a Danish context. A Danish model for collaborative care treatment of people with depression, generalized anxiety disorder, social phobia and panic disorder (the Collabri Model) is developed. The Collabri model consists of a multi-professional approach to treatment, scheduled monitoring and review, enhanced inter-professional communication and a structured treatment plan. Objectives: to investigate the effect of the Collabri model for depression and further investigate two methods for detection of depression; standard detection and case finding. Methods: Two researcher-blinded cluster-randomized controlled studies with an intervention group (treatment according to the Collabri model) and a control group (TAU). Participants are 480 patients with depression consulting their general practitioner. Results: Primary outcome for the collaborative care study on depression is depression symptoms, measured with BDI at 6 months. Discussion: The results will contribute new knowledge on collaborative care for depression and anxiety in Danish conditions.

Conditions

• Depression

Interventions

Type	Name	Description
OTHER	Treatment according to the Collabri model	The Collabri Model is a complex intervention and consists of a number of treatment modalities. The Collabri Model includes the following elements: A multi-professional approach to treatment including a care manager, scheduled monitoring and review, enhanced inter-professional communication and a structured treatment plan. It further integrates: Recruitment of staff with psychiatric experience, training of general practitioner and care manager, use of instruments for detection and follow-up, education and treatment of the patient, supervision from a psychiatric specialist, guided self-help, patient- and relative involvement and a stepped care approach to treatment where treatment is always commenced on the least invasive and least resource-demanding level.

Timeline

• Start date: 2014-11-01
• Primary completion: 2017-07-01
• Completion: 2020-07-01
• First posted: 2016-02-10
• Last updated: 2026-02-04

Locations

1 site across 1 country: Denmark