Clinical Trials Directory

Trials / Terminated

TerminatedNCT02658916

Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003

A Multicenter, Open-Label, Long-Term Treatment Study of Intravenously Administered BIIB092 in Patients With Progressive Supranuclear Palsy Who Participated in Study CN002003

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
47 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
41 Years – 86 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the long-term safety and tolerability of multiple intravenous (IV) infusions of BIIB092 in participants with Progressive Supranuclear Palsy (PSP). The study will also assess the pharmacodynamic (PD) effects of BIIB092 on cerebrospinal fluid (CSF) N-terminal tau, pharmacokinetics (PK), and immunogenicity of BIIB092 in participants with PSP.

Detailed description

This study, previously posted by Bristol-Myers Squibb, has transitioned to Biogen under a licensing agreement.

Conditions

Interventions

TypeNameDescription
DRUGBIIB092Same dose as corresponding CN002003 study panel.

Timeline

Start date
2016-02-22
Primary completion
2020-03-31
Completion
2020-03-31
First posted
2016-01-20
Last updated
2020-05-18

Locations

13 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT02658916. Inclusion in this directory is not an endorsement.

Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003 (NCT02658916) · Clinical Trials Directory