NCT02592408

A Study to Assess Current Standard Malaria Treatment Guidelines in the Republic of the Sudan

A Study to Assess Current Standard Malaria Treatment Guidelines and Evaluate Recently Developed G6PD Diagnostic Tools in the Republic of the Sudan

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 320 (actual)
• Sponsor: Menzies School of Health Research · Academic / Other
• Sex: All
• Age: 12 Months
• Healthy volunteers: Not accepted

Summary

This is a randomized controlled trial to assess the efficacy and safety of the national malaria treatment guidelines, asses the efficacy and safety of artesunate and sulphadoxine - pyrimethamine (AS+SP) for treatment in uncomplicated P. falciparum and P. vivax malaria and the hematologic effect of 14 days routine primaquine based radical cure in patients suffering from a P. vivax or mixed infection.

Conditions

• Malaria

Interventions

Type	Name	Description
DRUG	ASP	3 days of artesunate sulfadoxine/pyrimethamine on days 0-2
DRUG	SDPQ	single dose primaquine on day 2
DRUG	14DPQ	14 day primaquine starting on day 2
DRUG	14DPQ on Day 42	14 day primaquine starting on day 42

Timeline

• Start date: 2015-11-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2015-10-30
• Last updated: 2017-02-01

Locations

2 sites across 1 country: Sudan