NCT02591407

Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery

A Prospective Randomized Clinical Trial Comparing the Transversus Abdominis Plane Block (TAP) Versus Epidural Anesthesia For Enhanced Recovery Pathway Perioperative Management of Pain in Elective Colorectal Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Trinity Health Michigan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary outcome for this study is the Numeric Pain Score (NPS) for elective patients undergoing elective colorectal surgery that have been randomized to transversus abdominis plane block or epidural anesthesia for the management of perioperative pain in elective colorectal surgery.

Detailed description

Adequate peri-operative analgesia is a vital component of post-operative management for patients undergoing colon and rectal surgery, affecting hospital length of stay, quality of life, and patient outcomes. There are many options for the peri-operative management of pain after elective colorectal surgery. This is a randomized clinical trial comparing the transversus abdominis plane block using Exparel® to epidural anesthesia for the enhanced recovery pathway perioperative management of pain for elective colorectal surgery.

Conditions

• Colon Cancer
• Rectal Cancer
• Colonic Diverticulosis

Interventions

Type	Name	Description
PROCEDURE	TAP Block	This is a one time injection of Exparel in the plane between the internal oblique and transversus abdominis muscles
PROCEDURE	Continuous Epidural Analgesia	Epidural catheter placed prior to the operation in the standard fashion

Timeline

• Start date: 2016-01-12
• Primary completion: 2017-12-31
• Completion: 2017-12-31
• First posted: 2015-10-29
• Last updated: 2026-01-28
• Results posted: 2026-01-28

Locations

1 site across 1 country: United States