NCT02561377

Effect of Resistance Training on Metabolic Control and Outcome in Prediabetes (NMR-based Metabonomics)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 276 (estimated)
• Sponsor: Nanjing University of Traditional Chinese Medicine · Academic / Other
• Sex: All
• Age: 45 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study evaluates the efficacy of a 12-month resistance training on metabolic control and reducing the risk of diabetes.

Detailed description

Most of exercise interventions involved aerobic exercises, investigators were not able to find a single long term study focusing on type 2 diabetes prevention with resistance training and aerobic exercise. It has been known that for those who have already had diabetes, resistance training can reduce insulin resistance and HbA1c level, improve lipid profile, and decrease blood pressure. Based on previous findings, investigators will evaluate how the different exercising interventions impact on insulin resistance, metabolic control, and the incidence and prevalence of diabetes in prediabetes population who receive 12 months of either resistant training or aerobic exercise. Further more, metabolomics approach will be introduced to detect biological markers,and therefore,to analyze the predictive values of metabolomics on long term outcomes of prediabetes population.

Conditions

• Prediabetic State

Interventions

Type	Name	Description
BEHAVIORAL	resistance training	Resistance training consisted of 6 different resistance exercises per session using elastic string, and each exercise progressed to 2-3 at maximum resistance lifted 8-10 times.
BEHAVIORAL	aerobic training	Aerobic training consisted of aerobic exercise and progressed from 15-20min/session at 60% maximum heart rate to 45-50min/session at 75% maximum heart rate.

Timeline

• Start date: 2015-09-01
• Primary completion: 2016-07-01
• Completion: 2016-09-01
• First posted: 2015-09-28
• Last updated: 2015-09-29

Locations

2 sites across 1 country: China