NCT02556320

Immunological and Viral Parameters in Patients Receiving Anti-epileptic Drugs

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University Hospital, Rouen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A recent study has shown that certain drug allergies were actually related to an immune system against certain viruses. The aim of the study is to evaluate, in patients taking antiepileptic drugs, if this treatment induces proliferation of these viruses and secondarily an immune response that would promote the development of a rash. In particular, will be studied whether these drugs can induce virus reactivation "dormant" in the immune system. This study will not affect the usual follow-up proposed by investigators, with the exception of some additional blood samples.

Conditions

• Epilepsy
• Drug Hypersensitivity Syndrome

Interventions

Type	Name	Description
DRUG	anti-epileptic drug	Patient who initiate anti-epileptic drug (sodium valproate, divalproate sodium, valpromide, lamotrigine, carbamazepine, oxcarbazepine, eslicarbazepine acetate)
BIOLOGICAL	Blood sampling	Blood sampling is done for Patient who initiate anti-epileptic drug (sodium valproate, divalproate sodium, valpromide, lamotrigine, carbamazepine, oxcarbazepine, eslicarbazepine acetate)

Timeline

• Start date: 2013-05-01
• Primary completion: 2015-08-01
• Completion: 2015-12-01
• First posted: 2015-09-22
• Last updated: 2016-01-25

Locations

1 site across 1 country: France