Clinical Trials Directory

Trials / Completed

CompletedNCT02541123

Evaluation of Biomarker Kinetics After Mild Brain Injury Trauma

A Prospective Evaluation of Uch-l1 and Gfap Biomarker Kinetics After Mild Brain Injury Trauma

Status
Completed
Phase
Study type
Observational
Enrollment
194 (actual)
Sponsor
Banyan Biomarkers, Inc · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objective of the clinical trial is to evaluate the effect of time on levels of Ubiquitin C-terminal Hydrolase-L1 (UCH-L1) and Glial Fibrillary Acidic Protein (GFAP) biomarker levels in a population of head injured subjects over the age of 18 presenting acutely with a Glasgow Coma Scale score 13-15 as well as in a group of uninjured control subjects.

Conditions

Interventions

TypeNameDescription
OTHERBlood drawInitial draw followed by additional blood draws every 4 hours thereafter, up to 24 hours from the initial blood draw (not to exceed 7 blood draws). Follow up blood draw at Day 7. Control group only undergoes 2 blood draws 4 hours apart on Day 1.

Timeline

Start date
2016-01-01
Primary completion
2017-02-28
Completion
2017-02-28
First posted
2015-09-04
Last updated
2020-12-16

Locations

10 sites across 3 countries: United States, Germany, Hungary

Source: ClinicalTrials.gov record NCT02541123. Inclusion in this directory is not an endorsement.