Clinical Trials Directory

Trials / Completed

CompletedNCT02537574

Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Prior to First Dose of VIVITROL® (Naltrexone for Extended-Release Injectable Suspension)

A Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Prior to First Dose of VIVITROL®

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
380 (actual)
Sponsor
Alkermes, Inc. · Industry
Sex
All
Age
18 Years – 60 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the safety, effectiveness and tolerance of low doses of oral naltrexone along with buprenorphine to treat opioid use disorder prior to the first injection of VIVITROL.

Conditions

Interventions

TypeNameDescription
DRUGNTX/BUPDaily doses
DRUGNTX/PBO-BDaily doses
DRUGPBO-N/PBO-BDaily doses

Timeline

Start date
2015-08-01
Primary completion
2016-10-27
Completion
2017-01-09
First posted
2015-09-01
Last updated
2019-03-06
Results posted
2019-01-09

Locations

20 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02537574. Inclusion in this directory is not an endorsement.