Clinical Trials Directory

Trials / Terminated

TerminatedNCT02527681

Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibiotics

An Open-label Study to Evaluate the Single-dose Pharmacokinetics and Safety of Ceftobiprole in Neonate and Infant Subjects Aged up to 3 Months Undergoing Treatment With Systemic Antibiotics

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
15 (actual)
Sponsor
Basilea Pharmaceutica · Industry
Sex
All
Age
3 Months
Healthy volunteers
Not accepted

Summary

This study characterized the pharmacokinetics and safety of a single dose of ceftobiprole in neonates and infants aged ≤ 3 months.

Conditions

Interventions

TypeNameDescription
DRUGCeftobiprole medocarilCeftobiprole medocaril was administered as a single intravenous infusion, with a bodyweight-adjusted volume, at a constant rate over 4 hours. The ceftobiprole dose was 7.5 mg/kg, which corresponds to 10.0 mg ceftobiprole medocaril.

Timeline

Start date
2016-11-22
Primary completion
2020-02-25
Completion
2020-02-25
First posted
2015-08-19
Last updated
2023-06-05
Results posted
2021-01-06

Locations

14 sites across 6 countries: United States, Belgium, Germany, Latvia, Lithuania, Poland

Regulatory

Source: ClinicalTrials.gov record NCT02527681. Inclusion in this directory is not an endorsement.