Trials / Completed
CompletedNCT02522325
Reinforcing Effects of Cocaine During Phendimetrazine Maintenance
Behavioral Effects of Drugs (Inpatient): 31 (Cocaine and Phendimetrazine)
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- William Stoops · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This study will determine the initial efficacy of phendimetrazine as a pharmacotherapy for cocaine dependence. A rigorous, inpatient human laboratory study will be conducted in which the subjective, physiological and reinforcing effects of cocaine are evaluated during maintenance on placebo and phendimetrazine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Phendimetrazine | Phendimetrazine will be administered in divided doses twice daily. |
| DRUG | Cocaine | Intranasal cocaine will be administered during experimental sessions. |
| DRUG | Placebo | Placebo capsules will contain only cornstarch. |
Timeline
- Start date
- 2015-08-01
- Primary completion
- 2018-12-01
- Completion
- 2018-12-01
- First posted
- 2015-08-13
- Last updated
- 2019-07-02
- Results posted
- 2019-07-02
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02522325. Inclusion in this directory is not an endorsement.