NCT02503384

Clinical and Basic Study for Pediatric Liver Transplantation

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 180 (estimated)
• Sponsor: RenJi Hospital · Academic / Other
• Sex: All
• Age: 1 Month – 17 Years
• Healthy volunteers: Not accepted

Summary

Background: In mainland China, the development of pediatric liver transplantation (LT) has lagged behind that of adult LT during the past two decades, but it has been progressing immensely in recent years. Renji hospital(shanghai) is currently the largest pediatric transplant center in mainland China. Aim and method: This study is performed for establishment of key techniques for pediatric LT in mainland China, including the indications and timing for pediatric LT, the criteria for donor selections, living donor LT planning, prevention and treatment for posttransplant complications, long-term follow-up management et al.

Detailed description

Outcome measures: * Annual caseloads of pediatric liver transplantation * Patient survival: 1-, 3- and 5-year patient survival after liver transplantation * Graft survival: 1-, 3- and 5-year graft survival after liver transplantation * Posttransplant complications, such as biliary complications, vascular complications, acute rejections, infections et al. * Perioperative data, such as duration of operations, postoperative hospital stay et al. * Clinical data for living donors.

Conditions

• Biliary Atresia
• Metabolic Disorders
• Fulminant Liver Failure
• Hepatic Tumors

Timeline

• Start date: 2015-07-01
• Primary completion: 2018-07-01
• Completion: 2018-09-01
• First posted: 2015-07-21
• Last updated: 2015-07-21

Locations

1 site across 1 country: China