NCT02497729

Checklists and Upright Positioning in Endotracheal Intubation of Critically Ill Patients (Check-UP) Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 260 (actual)
• Sponsor: Vanderbilt University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The use of a written, pre-procedure checklist and positioning the patient with the head of the bed elevated have been proposed as interventions capable of preventing complications during non-elective intubation and are used intermittently in routine care -- however neither have been examined in a prospective trial.

Detailed description

Endotracheal intubation is common in the care of critically ill patients. Procedural complications including hypoxia and hypotension are frequent in urgent and emergent intubation and associated with an increased risk of death. The use of a written, pre-procedure checklist and positioning the patient with the head of the bed elevated have been proposed as interventions capable of preventing complications during non-elective intubation and are used intermittently in routine care -- however neither have been examined in a prospective trial. The investigators propose a randomized trial comparing use of a written checklist versus no written checklist and ramped versus sniffing position for endotracheal intubation of critically ill adults.

Conditions

• Respiratory Failure

Interventions

Type	Name	Description
PROCEDURE	Written Checklist	Use of a written checklist pre and peri-intubation
PROCEDURE	Head of Bed Up	Raising the patient's head of bed to 25 degrees

Timeline

• Start date: 2015-07-01
• Primary completion: 2016-09-01
• Completion: 2016-09-01
• First posted: 2015-07-14
• Last updated: 2016-09-19

Locations

5 sites across 1 country: United States