Clinical Trials Directory

Trials / Completed

CompletedNCT02479802

Efficacy and Safety of Plasma Exchange With Albumin in Patients With Amyotrophic Lateral Sclerosis

Pilot Study on the Effects of Plasma Exchange on Motor Dysfunction and Cognitive Function in Patients With Amyotrophic Lateral Sclerosis

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
13 (actual)
Sponsor
Instituto Grifols, S.A. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Pilot, phase II, prospective, open-label, uncontrolled study of plasma exchange with 5% albumin in 10 subjects having a definite, possible, or probable diagnosis of Amyotrophic Lateral Sclerosis (ALS).

Conditions

Interventions

TypeNameDescription
BIOLOGICALAlbumin27 plasma exchange procedures using Albumin 5% (estimated 3000 mL per plasma exchange) as replacement solution: * three weeks of intensive treatment with two plasma exchanges per week * twenty-one weeks of maintenance treatment with one weekly plasma exchange

Timeline

Start date
2014-11-01
Primary completion
2016-06-01
Completion
2016-06-01
First posted
2015-06-24
Last updated
2020-06-16
Results posted
2020-06-16

Locations

1 site across 1 country: Spain

Source: ClinicalTrials.gov record NCT02479802. Inclusion in this directory is not an endorsement.