Clinical Trials Directory

Trials / Completed

CompletedNCT02460679

Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS)

A Phase 2A Safety and Biomarker Study of EPI-589 in Subjects With Amyotrophic Lateral Sclerosis

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
19 (actual)
Sponsor
PTC Therapeutics · Industry
Sex
All
Age
21 Years – 70 Years
Healthy volunteers
Not accepted

Summary

This is an open label study with 30-day run in phase to establish baseline parameters, 90-day treatment phase, and a 90-day withdrawal phase to determine long-term effects, duration of treatment response, and potential effects of EPI-589 therapy on known trajectory.

Conditions

Interventions

TypeNameDescription
DRUGEPI-589An immediate release film-coated table at a 250 mg dosage strength will be administered per dose and schedule specified in arm.

Timeline

Start date
2016-01-14
Primary completion
2018-02-23
Completion
2018-02-23
First posted
2015-06-02
Last updated
2020-10-14
Results posted
2020-09-23

Locations

3 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02460679. Inclusion in this directory is not an endorsement.

Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS) (NCT02460679) · Clinical Trials Directory