NCT02455154

Traditional Chinese Medicine as Preventive Method for Osteoporosis Induced by Adjuvant Endocrine Therapy

Traditional Chinese Medicine as Preventive Method for Osteoporosis in Early Breast Cancer Patients Receiving Adjuvant Endocrine Therapy

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 278 (actual)
• Sponsor: Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To test the efficacy of two Traditional Chinese Medicine in preventing osteoporosis in patients receiving adjuvant endocrine therapy.

Detailed description

Breast cancer is the most common malignant tumor in female wolrdwide. Results from clinical trials like ATAC trial have demonstrated the efficacy of AIs in postmenopausal breast cancer patients. Meanwhile it may cause a certain rate of osteoporosis in postmenopausal patients. The aim of this trial is to test the efficacy of two traditional Chinese medicine in preventing osteoporosis in patients receiving adjuvant endocrine therapy.

Conditions

• Breast Cancer
• Osteoporosis

Interventions

Type	Name	Description
DRUG	Letrozole	Letrozole endocrine therapy for 2.5mg qd po.
DRUG	Zhongyaofufang	Traditional Chinese Medicine for patients with Osteoporosis
DRUG	Xianlinggubao	Traditional Chinese Medicine for patients with Osteoporosis

Timeline

• Start date: 2015-05-01
• Primary completion: 2019-02-01
• Completion: 2019-09-01
• First posted: 2015-05-27
• Last updated: 2020-04-14

Locations

1 site across 1 country: China