Clinical Trials Directory

Trials / Completed

CompletedNCT02451007

Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization in Patients With Selected Solid Tumors

Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization (QTc Duration) in Patients With Selected Solid Tumors

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
39 (actual)
Sponsor
PharmaMar · Industry
Sex
All
Age
65 Years
Healthy volunteers
Not accepted

Summary

Study to assess the potential effects of lurbinectedin (PM01183) at a therapeutic dose on the duration of the QTc interval, measured by electrocardiograms (ECGs), to characterize the PM01183 plasma concentration/QTc relationship, and to explore related ECG parameters in patients with selected solid tumors.

Conditions

Interventions

TypeNameDescription
DRUGlurbinectedin (PM01183)

Timeline

Start date
2015-08-12
Primary completion
2016-08-19
Completion
2016-08-19
First posted
2015-05-21
Last updated
2019-11-19
Results posted
2019-02-18

Locations

16 sites across 2 countries: United States, Spain

Source: ClinicalTrials.gov record NCT02451007. Inclusion in this directory is not an endorsement.

Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization in Patients With Selected Solid Tumors (NCT02451007) · Clinical Trials Directory