NCT02447744

Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 19 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Childhood trauma is remarkably prevalent, and it has long lasting impact on mental health and neural development. This trial aims to see whether the 8-week mindfulness based intervention can reduce stress related psychological symptoms for young adults with childhood maltreatment, and whether it can promote neural plasticity.

Detailed description

This study recruits young adults with childhood adversity; enrolled subjects either receive an 8-week mindfulness based intervention, or wait for 8 weeks before receiving the intervention. MRI and a battery of self report questionnaires will be administered before and after the intervention; subjects on the waiting list will undergo the same research procedures at the same time as subjects in the intervention group. Primary hypotheses include improved hippocampal plasticity, increased mindfulness and reduced stress and related psychological symptoms.

Conditions

• Depression
• Anxiety
• PTSD
• Trauma, Psychological

Interventions

Type	Name	Description
BEHAVIORAL	Mindfulness based intervention	The intervention is an 8-week structured mindfulness based behavioral intervention program that teaches mindfulness meditation, mindful yoga and psychological knowledge about stress.

Timeline

• Start date: 2014-08-01
• Primary completion: 2016-07-21
• Completion: 2016-07-21
• First posted: 2015-05-19
• Last updated: 2021-03-23
• Results posted: 2021-03-23

Locations

1 site across 1 country: United States