NCT02439242

Correlation Between ΔPP/HR and ΔSV During Fluid Challenge.

Correlation Between the Pulse Pressure / Heart Rate Ratio Variations and Stroke Volume Variations During Fluid Challenge.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University Hospital, Caen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In high perioperative risk patients, guidelines suggest intraoperative haemodynamic optimization by measurement of stroke volume (SV) to guide fluid resucitation.This strategy requires an invasive monitoring and learning. Some studies tried to find SV surrogates based on haemodynamic usual parameters. In an experimental hemorrhagic shock, SV was correlated to the pulse pressure (PP) / heart rate (HR) ratio. The investigators hypothesized that SV variations (ΔSV) would be correlated to the PP/HR ratio variations (ΔPP / HR) during fluid challenge, and ΔPP / HR would be able to detect a ΔSV greater than 10%.

Conditions

• Hypovolemia

Interventions

Type	Name	Description
DRUG	fluid challenge of saline	250 ml of saline

Timeline

• Start date: 2014-06-01
• Primary completion: 2015-11-01
• Completion: 2015-11-01
• First posted: 2015-05-08
• Last updated: 2015-05-08

Locations

1 site across 1 country: France