NCT02432781

Oral Carbohydrate in DM Patients Undergoing Total Knee Arthroplasty

Effect of Preoperative Oral Carbohydrates on Postoperative Nausea and Vomiting and Quality of Recovery in DM Patients Undergoing Total Knee Arthroplasty

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 82 (actual)
• Sponsor: Severance Hospital · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

The primary purpose of this study is to investigate the effects of carbohydrate-rich drink on postoperative nausea and vomiting in diabetic patients undergoing total knee arthroplasty. The secondary purpose is to investigate the effects of carbohydrate-rich drink on quality of recovery and inflammation in diabetic patients after total knee arthroplasty.

Detailed description

Carbohydrate-rich drink has been proved to neither delay gastric emptying nor affect gastric acidity and is therefore considered safe to use in elective surgical patients without risk factors for pulmonary aspiration. It reduced postoperative nausea and vomiting and improved sense of well-being after surgery. Moreover, carbohydrate-rich drink was not found to be affected by delayed gastric emptying in patients with uncomplicated type 2 diabetes. Therefore, carbohydrate drink may be safely administered 3 h before anesthesia without risk of hyperglycemia or aspiration.

Conditions

• Total Knee Arthroplasty

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Carbohydrate-rich drink
DIETARY_SUPPLEMENT	10% dextrose solution mixed with insulin 16 unit 100 mL/h

Timeline

• Start date: 2015-06-25
• Primary completion: 2017-12-14
• Completion: 2017-12-14
• First posted: 2015-05-04
• Last updated: 2018-09-06

Locations

1 site across 1 country: South Korea