Clinical Trials Directory

Trials / Completed

CompletedNCT02404740

Noninvasive Intracranial Pressure and Hydrocephalus Patients

Continuous Noninvasive Estimation of Intracranial Pressure to Assess Ventriculoperitoneal Shunt Malfunction in Patients With Hydrocephalus

Status
Completed
Phase
Study type
Observational
Enrollment
163 (actual)
Sponsor
University of Colorado, Denver · Academic / Other
Sex
All
Age
31 Days – 35 Years
Healthy volunteers
Not accepted

Summary

Using a pulse oximeter, we have developed an algorithm that estimates intracranial pressure (ICP) based on patients who have had traumatic brain injuries. Patients with hydrocephalus are typically treated with a shunt in order to reduce ICP. At times the shunt can malfunction. We believe that our algorithm will help identify when a hydrocephalus patient's shunt has malfunctioned.

Detailed description

A malfunctioning ventriculoperitoneal (VP) shunt will typically cause a rise in intracranial pressure, which can be difficult to identify without costly imaging. Novel, state-of-the art machine learning techniques can be leveraged to develop an algorithm that noninvasively estimates intracranial pressure. The resulting algorithm will accurately determine the presence or absence of ventriculoperitoneal shunt malfunction in patients with hydrocephalus.

Conditions

Interventions

TypeNameDescription
DEVICEPulse oximetryPulse oximetry

Timeline

Start date
2015-02-01
Primary completion
2018-09-01
Completion
2018-09-01
First posted
2015-03-31
Last updated
2019-10-04

Source: ClinicalTrials.gov record NCT02404740. Inclusion in this directory is not an endorsement.