Trials / Unknown
UnknownNCT02399878
Intra-operative Inspiratory Oxygen Fraction and Postoperative Respiratory Complications
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 70,000 (estimated)
- Sponsor
- Massachusetts General Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Respiratory complications represent the second most frequent type of postoperative complications with an incidence estimated to range from 2.0% to 7.9% It has been shown that intra-operative protective ventilation is associated with a reduced risk of respiratory complications. The effects of intra-operative inspiratory oxygen fraction (FiO2) remain to be investigated. In this study, the investigators aim to investigate the association between intra-operative FiO2 and respiratory complication as well as surgical site infection and ICU admission in patients undergoing non-cardiothoracic surgery. The investigators primary hypothesis is that high intra-operative FiO2 increases the risk of postoperative respiratory complications independent of predefined risk factors.
Conditions
- Respiratory Failure
- Acute Respiratory Failure Requiring Intubation
- Pulmonary Edema
- Pneumonia
- Surgical Wound Infection
- Mortality
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Inspiratory oxygen |
Timeline
- Start date
- 2007-01-01
- Primary completion
- 2014-08-01
- First posted
- 2015-03-26
- Last updated
- 2016-03-31
Source: ClinicalTrials.gov record NCT02399878. Inclusion in this directory is not an endorsement.