Trials / Withdrawn
WithdrawnNCT02394418
Effect of Sevoflurane, Propofol and Dexmedetomidine on Delirium & Neuroinflammation in Mechanically Ventilated Patients
Comparison of Sedative Effects of Sevoflurane, Propofol and Dexmedetomidine on the Clinical Course of Delirium and Neuroinflammation in Mechanically Ventilated Patients
- Status
- Withdrawn
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI) · Other Government
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Assessment of sedative effects of sevoflurane, dexmedetomidine and propofol on the clinical course of delirium, SIRS and neuroinflammation in mechanically ventilated patients using CAM-ICU scale, GSK-3beta and protein S100b in serum.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sevoflurane | Treatment of delirium by inhaled sevoflurane |
| DRUG | Propofol | Treatment of delirium by propofol i.v. infusion |
| DRUG | Dexmedetomidine | Treatment of delirium by dexmedetomidine i.v. infusion |
Timeline
- Start date
- 2017-09-01
- Primary completion
- 2018-05-01
- Completion
- 2018-08-01
- First posted
- 2015-03-20
- Last updated
- 2019-08-15
Source: ClinicalTrials.gov record NCT02394418. Inclusion in this directory is not an endorsement.