Trials / Completed
CompletedNCT02389829
Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute Migraine
Hydromorphone Versus Prochlorperazine + Diphenhydramine for Treatment of Acute Migraine. A Randomized, Emergency Department Based, Comparative Efficacy Study
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 127 (actual)
- Sponsor
- Montefiore Medical Center · Academic / Other
- Sex
- All
- Age
- 21 Years
- Healthy volunteers
- Not accepted
Summary
Opioids are commonly used to treat migraine in North American Emergency Departments. We are comparing efficacy and adverse events of hydromorphone, an opioid, to that of prochlorperazine, a dopamine antagonist with known efficacy in migraine. Prochlorperazine will be combined with diphenhydramine to prevent adverse events.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Hydromorphone | |
| DRUG | Prochlorperazine | |
| DRUG | Diphenhydramine |
Timeline
- Start date
- 2015-03-01
- Primary completion
- 2016-06-01
- Completion
- 2016-10-01
- First posted
- 2015-03-17
- Last updated
- 2018-08-31
- Results posted
- 2018-06-06
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02389829. Inclusion in this directory is not an endorsement.