NCT02378454

Multiple Breath Nitrogen Washout in Healthy and Cystic Fibrosis Children

Multiple Breath Nitrogen Washout in Healthy and Cystic Fibrosis Children: A Comparison of Two Commercially Available Devices

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: All
• Age: 5 Years – 18 Years
• Healthy volunteers: Accepted

Summary

This study compares the lung clearance index (LCI) in cystic fibrosis and healthy children obtained with two different multiple breath nitrogen washout (MBWN2) devices. Each participants will perform the test (LCI) in duplicate on each device.

Detailed description

Using nitrogen as the inert gas, there are currently two commercially available devices that offer the possibility to measure the LCI. However, comparison between them are lacking. The 2 MBWN2 devices are the "EasyOne Pro Lab" (ndd Medical Technologies, Zürich, Switzerland) and the "Exhalyzer D" (Eco Medics AG, Duernten, Switzerland).

Conditions

• Cystic Fibrosis
• Healthy

Interventions

Type	Name	Description
DEVICE	Comparison of two MBWN2 devices : "EasyOne Pro Lab" versus "Exhalyzer D"	Healthy and Cystic Fibrosis participants will perform the same day MBWN2 tests in duplicate with each device.

Timeline

• Start date: 2014-08-01
• Primary completion: 2015-04-01
• Completion: 2015-04-01
• First posted: 2015-03-04
• Last updated: 2015-07-30

Locations

1 site across 1 country: Belgium