Clinical Trials Directory

Trials / Terminated

TerminatedNCT02370823

A Controlled Surveillance of the Osteoarthritic Knee Microenvironment With Regenexx® SD Treatment

Status
Terminated
Phase
Study type
Observational
Enrollment
20 (estimated)
Sponsor
Regenexx, LLC · Industry
Sex
All
Age
35 Years – 85 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to determine the levels of proteins and/or cellular components of the synovial fluid that are indicative of microenvironment phenotypes of the osteoarthritic knee compared to unilateral unaffected joints pre-injection to 6 weeks post-Regenexx® SD treatment.

Detailed description

The primary objective of this study is to determine the levels of proteins and/or cellular components of the synovial fluid that are indicative of microenvironment phenotypes of the osteoarthritic knee compared to unilateral unaffected joints pre-injection to 6 weeks post-Regenexx SD treatment (day 0). Secondary objective is an evaluation of possible direct and/or indirect associations between the measured levels of proteins and/or cellular components of the synovial fluid in the osteoarthritic knee joint with the administration of the Regenexx SD treatment. The secondary objective will include MRI evidence of cartilage repair; incidence of post-operative complications, adverse events, re-injections, and surgical intervention; change in pain score and use of pain medications.

Conditions

Interventions

TypeNameDescription
PROCEDURERegenexx SDstem cell treatment

Timeline

Start date
2015-02-01
Primary completion
2018-03-01
Completion
2018-03-01
First posted
2015-02-25
Last updated
2018-03-30

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02370823. Inclusion in this directory is not an endorsement.