NCT02363348

Efficacy and Safety of L Arginine to Prevent Preeclampsia

Efficacy and Safety of L Arginine to Prevent Preeclampsia in High Risk Pregnancies

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 96 (actual)
• Sponsor: Hospital Civil Juan I. Menchaca · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Randomized double-blind controled clinical trial to assess the efficacy and safety of L-arginine to prevent preeclampsia. applied to pregnant women with risk factors for preeclampsia. the main result was the development of preeclampsia as well as side effects to taking l arginine besides perinatal outcomes

Detailed description

Two groups were formed. one received L arginine 3 grams orally at day from the 20th week of pregnancy. the other group received placebo. Each three weeks were evaluated in search of high blood pressure and proteinuria. The follow-up was until the end of pregnancy and two weeks after this

Conditions

• Preeclampsia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	L arginine	L arginine is a basic amino-acid precursor of nitric oxide main vasodilator.
OTHER	Placebo	calcined magnesia

Timeline

• Start date: 2010-08-01
• Primary completion: 2013-08-01
• Completion: 2014-03-01
• First posted: 2015-02-16
• Last updated: 2016-03-04

Locations

1 site across 1 country: Mexico