NCT02360228

STimulation to Improve Auditory haLLucinations

Targeting Auditory Hallucinations With Alternating Current Stimulation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: University of North Carolina, Chapel Hill · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Investigating the effects of non-invasive transcranial current stimulation as a treatment for auditory hallucinations in patients with schizophrenia.

Detailed description

The investigator's primary objective is to conduct a pilot clinical trial to establish the feasibility and to collect first effectiveness data for the use of transcranial alternating current stimulation (tACS) to re-normalize pathological alpha oscillations in dorso-lateral prefrontal cortex (dl-PFC) of patients with schizophrenia or schizoaffective disorder by comparing Auditory Hallucination Rating Scale (AHRS) scores immediately before the first stimulation session and immediately after the last stimulation session. As a secondary objective the investigators will assess the differential clinical effects of sham, 10 Hz and 2 mA transcranial direct current stimulation (tDCS) on electroencephalogram (EEG) measures of alpha oscillations.

Conditions

• Schizophrenia
• Schizoaffective Disorder

Interventions

Type	Name	Description
DEVICE	tACS (alpha)
DEVICE	tDCS

Timeline

• Start date: 2015-05-01
• Primary completion: 2017-02-01
• Completion: 2017-02-01
• First posted: 2015-02-10
• Last updated: 2018-04-27
• Results posted: 2018-04-27

Locations

1 site across 1 country: United States