NCT02354677

Repair, Remodeling and Regeneration of the Bronchial Epithelium of COPD Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University Hospital, Montpellier · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

COPD is characterized by exagerated decline FEV1 related to obstructive non reversible airflow. This could be the consequence of structural changes and inflammatory pattern of the bronchial wall. Lesions could lead to normal but also abnormal remodeling specially in COPD including a decrease in Club cells number and function.There is no treatment actually available targeted to a normal repair of the epithelium. The objective of this work is to identify potential targets for reprograming bronchial epithelial cells I order to achieve a good repair.

Conditions

• Heathy Volunteers
• Smokers
• COPD

Interventions

Type	Name	Description
OTHER	In vitro experiments on bronchial epithelial cells

Timeline

• Start date: 2014-10-17
• Primary completion: 2018-04-17
• Completion: 2018-04-17
• First posted: 2015-02-03
• Last updated: 2019-09-24

Locations

1 site across 1 country: France